Walter Lee MurfeeAssistant Professor of Biomedical Engineering Email: wmurfee@tulane.edu 530 Lindy Boggs Building |
Massachusetts Institute of Technology, Cambridge, MA. B.S. 1999 Mechanical Engineering
University of Virginia, Charlottesville, VA. Ph.D. 2005 Biomedical Engineering
University of California - San Diego, La Jolla, CA. 2005-2007 Postdoctoral Fellowship
My primary research aim is to apply in vivo, in vitro, and computational bioengineering approaches to better understand the regulation of adult microvascular patterning and the functional relationships between microvascular remodeling and other network remodeling processes such as neurogenesis and lymphangiogenesis. Associated active areas of interest include perivascular cell lineage and dynamics, the importance for arterial/venous identity, the influence of local hemodynamics, and altered microvascular network patterns associated with hypertension. In general, the work in my laboratory will provide valuable insight for the engineering of functional vascularized tissues and for understanding vascular dysfunction associated with multiple pathological conditions, such as hypertension, tumor growth, and wound healing.
August Krogh Young Investigator Travel Award, The Microcirculatory Society (2007) Benjamin Zweifach Student Award, The Microcirculatory Society (2005) Student Elected Teaching Assistant Award, Department of Biomedical Engineering, University of Virginia (2005)
Murfee WL, Rappleye JW, Ceballos M, Schmid-Schonbein GW. Discontinuous Expression of Endothelial Cell Adhesion Molecules along Initial Lymphatic Vessels in Adult Rat Mesentery: The Primary Valve Structure. Lymphatic Research and Biology, In Press, 2007.
Binder KW, Murfee WL, Song J, Laughlin MH, Price RJ. Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Remodeling in Interval Sprint Trained Skeletal Muscle. Microcirculation, 14: 181-192, 2007.
Taylor AC, Murfee WL, Peirce SM. EphB4 Expression along Adult Microvascular Networks: More than a Venous Specific Marker. Microcirculation, 14: 253-267, 2007.
Murfee WL, Rehorn MR, Peirce SM, Skalak TC. Perivascular Cells along Venules Upregulate NG2 Expression During Microvascular Remodeling. Microcirculation, 13: 261-273, 2006.
Murfee WL, Hammett LA, Evans C, Xie L, Squire M, Rubin C, Judex S, Skalak TC. High-Frequency Low Magnitude Vibrations Suppress the Number of Blood Vessels per Muscle Fiber in Mouse Soleus Muscle. Journal of Applied Physiology, 98: 2376-2380, 2005.
Murfee WL, Skalak TC, Peirce SM. Differential Arterial/Venous Expression of NG2 Proteoglycan in Perivascular Cells Along Microvessels: Identifying a Venule-Specific Phenotype. Microcirculation, 12(2): 151-160, 2005.
Murfee WL, Van Gieson EJ, Price RJ, Skalak TC. Cell Proliferation in Mesenteric Microvascular Network Remodeling in Response to Elevated Hemodynamic Stress. Annals of Biomedical Engineering, 32(12): 1662-1666, 2004.
